Table 3:

Primary Endpoint by Demographic, Severity of Disease, and Virologic Subgroups

Subgroup	N	Percentage in Group	Proportional Odds Ratio [95% CI]	p-value	P-value for treatment by subgroup interaction*
Age (category)
Adult	125	90.6	1.09 [0.56, 2.12]	0.8	0.41
Children	13	9.4	2.64 [0.36, 19.38]	0.34
Gender
Male	71	51.4	1.48 [0.60, 3.66]	0.4	0.59
Female	67	48.6	1.04 [0.43, 2.52]	0.93
Race
White	105	76.1	1.15 [0.56, 2.35]	0.7	0.75
Non-white	33	23.9	1.47 [0.39, 5.53]	0.57
Clinical Status at Day 0
Non-ICU no supplemental oxygen	23	16.7	1.22 [0.23, 6.35]	0.82	0.9
Non-ICU with supplemental oxygen	55	39.8	1.30 [0.46, 3.70]	0.62
In the ICU	60	43.5	1.74 [0.66, 4.62]	0.27
Baseline NEW/PEW Score
Below Median	76	55.9	1.27 [0.54, 2.96]	0.59	0.21
Above Median	60	44.1	3.01 [1.03, 8.81]	0.045
Duration of Symptoms
≤ 4 days	109	79.0	1.46 [0.72, 2.93]	0.29	0.88
> 4 days	29	21.0	1.27 [0.25, 6.35]	0.77
Subgroup
A/H1N1	35	28.2	3.63 [0.96, 13.71]	0.058	0.12
A/H3N2	89	71.8	1.07 [0.49, 2.33]	0.86

^*the interaction p-values shown are not adjusted for multiple testing