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. Author manuscript; available in PMC: 2020 Jan 3.
Published in final edited form as: Biochemistry. 2019 Aug 26;58(36):3813–3822. doi: 10.1021/acs.biochem.9b00523

Table 1.

Minimum Inhibitory Concentrations and Fractional Inhibitory Values of 600 Da BPEI in Combination with Various Antibiotics against MRSAa

MRSA MW2 MRSA USA300 MRSA 252 MRSA 33592
MIC FICI MIC FICI MIC FICI MIC FICI
600-Da BPEI 64 - 32 - 32 - 32 -
oxacillin 32 0.250 32 0.266 >256 0.501 256 0.281
ampicillin 128 0.188 2 0.516 256 0.375 256 0.516
amoxicillin 128 0.250 4 0.5 256 0.500 256 0.375
piperacillin >256 0.266 16 0.313 >256 0.501 >256 0.501
imipenem 0.5 0.375 0.25 0.25 64 0.508 32 0.281
meropenem 2 0.313 4 0.250 32 0.504 8 0.563
ceftizoxime >256 0.156 256 0.313 >256 0.254 >256 0.5
cephalothin 4 0.5 2 0.5 32 0.281 32 0.375
vancomycin 1 1 1 1 1 1 2 0.504
linezolid 2 0.5 1 0.5 1 0.5 1 0.5
a

Each value is the average of three separate trials.