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. 2019 Dec 31;7:3. doi: 10.1051/rmr/190004

Table 1.

HH pathway modulators.

Factor effected Functions Modulators References (PMID)
HH Antagonist RU-SKI 39
RU-SKI41
RU-SKI43
RU-SKI 50
[81]
SHH Block 5E1 [26]
PC Antagonist CA1
CA2
[142]
SMO Antagonist DHCEO
SMANT
KAAD-cyclopamine, Jervine
Saridegib
Vitamin D3
SEN450
[101]
[137]
[113]
[12]
[123]
[10]
[29]
SMO Agonist SAG
Purmorphamine, Oxysterols
Cholesterol,
PI4P
GSA-10
[30]
[105]
[69]
[63]
[47]
[33]
GLI Antagonist Arsenic trioxide [7]