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. 2015 Mar 27;3(1):e38. doi: 10.15190/d.2015.30

Figure 2. Acute and chronic inflammation elements that are linked to tumorigenesis.

Figure 2

A. T and B lymphocytes secrete factors that induce M1 macrophage phenotype, enhance innate immunity, CTL-mediated destruction, activation of the antigen presenting capacity and NK cell activation. All these processes have a potent anti-tumorigenesis action; B. T and B lymphocytes secrete factors that induce M2 macrophage phenotype, enhance myeloid suppressor activity, reduce CTL activity, decrease antigen presenting capacity and NK cell activity. All these processes have a potent pro-tumorigenesis action.