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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Pediatr Blood Cancer. 2019 Apr 22;66(8):e27770. doi: 10.1002/pbc.27770

Figure 2. Large B-cell lymphoma with IRF4 rearrangement of the small intestine.

Figure 2.

A) H&E 20X demonstrating small intestinal mucosa overlying an atypical lymphoid proliferation. B) H&E 400X demonstrating atypical cells with irregular nuclear contours, coarse chromatin, and variably conspicuous nucleoli. C) >90% of atypical lymphocytes strongly expressed MUM1 (400X). The cells lacked CD10 and BCL2 expression. BCL6 staining failed. D) FISH demonstrated separated red and green probes from the IRF4 gene break-apart probe.