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. Author manuscript; available in PMC: 2020 May 4.
Published in final edited form as: Nat Microbiol. 2019 Nov 4;5(1):56–66. doi: 10.1038/s41564-019-0596-1

Extended Data Fig. 1. A four-member gut bacterial consortium is capable of converting dietary lignans to phytoestrogenic enterolignans.

Extended Data Fig. 1.

a, Time-course experiments exhibiting the conversion of PINO to ENL and the growth profile of each bacterium with the lignan it metabolizes. Due to the chemical instability of dmSECO, this compound could not be accurately measured. Red arrows indicate time at which culture was exposed to lignan. Lignan concentrations were measured by HPLC. Culture turbidity, measured as optical density at 600 nm (OD600), is plotted. Values are mean±SEM (n=3 biological replicates). b, Growth profiles of each bacterium cultured with and without lignan. Culture turbidity, measured as optical density at 600 nm (OD600), is plotted. Values are mean±SEM (n=3 biological replicates).