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Cytotoxicity activity of GemHCl and Gem-SLNs against 2D and 3D MIA-PaCa-2 and PPCL-46 cultures
| Formulation | IC50 (2D MIA-PaCa-2 Culture) (μM) | IC50 (3D MIA-PaCa-2 Culture) (μM) |
| GemHCl | 188 ± 46 | 254 ± 52 |
| Gem-SLN4 | 103 ± 3 | 194 ± 24 |
| Gem-SLN15 | 56 ± 16 | 127 ± 4 |
| Gem-SLN21 | 122 ± 6 | 220 ± 52 |
| IC50 (2D PPCL-46 Culture) (μM) | IC50 (3D PPCL-46 Culture) (μM) | |
| GemHCl | 126 ± 3 | 241 ± 3 |
| Gem-SLN15 | 27 ± 5 | 66 ± 2 |
