TABLE I.
Example studies using single-SNP-single-QT methods, where pairwise SNP-QT associations are examined on a SNP-by-SNP and QT-by-QT basis.
Ref | Notes |
---|---|
[45] | GWAS, targeted QT, linear regression |
[46] | GWAS, targeted QT, linear regression |
[48] | Targeted SNP, targeted QTs, two-way ANCOVA |
[49] | Targeted SNP, voxelwise QTs across brain, general linear model |
[37] | GWAS, ROI-based QTs across brain, linear regression |
[57] | GWAS, voxelwise QTs across brain, linear regression |
[50] | Fast voxelwise GWAS (FVGWAS): heteroscedastic linear model, global sure independence screening, wild bootstrap |
[52] | Regression models for analyzing secondary phenotypes |
[55] | Regression models for analyzing secondary phenotypes |