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Effects of Tat-CIAPIN1 protein on TPA-induced mice ear edema. Ears of mice were treated with TPA (1 μg/ear) once a day for 3 days. Tat-CIAPIN1 protein (10 μg) was topically applied to the mouse ears 1 h prior to TPA exposure over 3 days. Protective effects of Tat-CIAPIN1 protein were confirmed by hematoxylin and eosin staining, changes in ear weight, and ear thickness in a TPA-induced mice ear edema model. Scale bar = 50 μm. *P < 0.05, compared with TPA-treated mice.
