Table 1.
Baseline characteristics and clinical data of CAD group and NCAD group.
| Variables | CAD group (n=38) | NCAD group (n=40) | χ2/t | P |
|---|---|---|---|---|
| Demographics | ||||
| Age (years) | 63.5±5.8 | 61.1±7.7 | 1.531 | 0.130 |
| Sex (% male) | 24 (63.2%) | 20 (50.0%) | 1.372 | 0.241 |
| BMI (kg/m2) | 24.2±2.6 | 23.6±4.3 | 0.688 | 0.493 |
| Smoking | 0.535 | 0.765 | ||
| Non-smoker | 26 (68.4%) | 29 (72.5%) | ||
| Current smoker | 10 (26.3%) | 8 (20.0%) | ||
| Former smoker | 2 (5.3%) | 3 (7.5%) | ||
| NYHA functional class | 7.373 | 0.061 | ||
| I | 8 (21.1%) | 7 (17.5%) | ||
| II | 18 (47.4%) | 10 (25.0%) | ||
| III | 7 (18.4%) | 8 (20.0%) | ||
| IV | 5 (13.2%) | 15 (37.5%) | ||
| LVEF (%) | 54.3±6.5 | 52.3±6.2 | 1.354 | 0.180 |
| Comorbidities | ||||
| Hypertension | 7 (18.4%) | 5 (12.5%) | 0.525 | 0.541 |
| T2DM | 17 (44.7%) | 11 (27.5%) | 2.516 | 0.113 |
| Stroke | 2 (5.3%) | 4 (10.0%) | 0.616 | 0.433 |
| COPD | 4 (10.5%) | 4 (10.0%) | 0.006 | 0.939 |
| Dyslipidemia | 18 (47.4%) | 12 (30.0%) | 2.484 | 0.115 |
| Laboratory examination | ||||
| FBG (mmol/L) | 6.18±2.15 | 5.81±1.63 | 0.845 | 0.401 |
| HbAlc (%) | 5.55±1.32 | 5.68±1.23 | 0.425 | 0.672 |
| hs-CRP (mg/L) | 1.96±1.15 | 2.05±1.2 | 0.326 | 0.745 |
| BNP (pg/ml) | 177.24±168.46 | 254±205.36 | 1.800 | 0.076 |
| cTnI (μg/L) | 0.05±0.03 | 0.06±0.03 | 0.864 | 0.390 |
| Serum creatinine (μmol/L) | 75.89±25.67 | 72.95±25.82 | 0.505 | 0.615 |
| Triglycerides (mmol/L) | 1.55±0.24 | 1.44±0.36 | 1.579 | 0.118 |
| Total cholesterol (mmol/L) | 4.45±1.21 | 4.55±1.36 | 0.3424 | 0.733 |
| HDL-C (mmol/L) | 0.94±0.21 | 1.05±0.32 | 1.785 | 0.078 |
| LDL-C (mmol/L) | 3.19±1.04 | 3.01±1.21 | 0.703 | 0.484 |
| Medications | ||||
| Aspirin (%) | 20 (52.6%) | 1 (2.5%) | 24.892 | <0.001 |
| Statins (%) | 14 (36.8%) | 8 (20.0%) | 2.730 | 0.099 |
| Nitrates (%) | 35 (92.1%) | 4 (10.0%) | 52.547 | <0.001 |
| ACEI/ARB (%) | 7 (18.4%) | 5 (12.5%) | 0.525 | 0.469 |
| β-blockers (%) | 5 (13.2%) | 3 (7.5%) | 0.556 | 0.456 |
| Major heart disease | NA | NA | ||
| CAD | 38 | 0 | ||
| Valve disease | 0 | 21 | ||
| Congenital heart disease | 0 | 19 | ||
BMI – body mass index; NYHA – New York Heart Association; LVEF – left ventricular ejection fraction; T2DM – type 2 diabetes mellitus; COPD – chronic obstructive pulmonary disease; FBG – fasting blood glucose; HbAlc – glycated hemoglobin; hs-CRP – hypersensitive C-reactive protein; BNP – brain natriuretic peptide; HDL-C – high-density lipoprotein cholesterol; LDL-C – low-density lipoprotein cholesterol; ACEI/ARB – angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers; CAD – coronary artery disease.