Table 3.

Uni- and multivariate Cox proportional-hazards analysis of clinicopathological factors (overall survival)

Characteristics	Number	Univariate			Multivariate
		HR	95% CI	P value	HR	95% CI	P value
Expression of GGH				0.02			0.006
Low	42	1.00			1.00
High	211	2.27	1.14–4.51		2.65	1.32–5.31
Expression of FPGS				0.43
Low	42	1.00
High	211	1.27	0.71–2.28
Age(years)				0.81
< 65	135	1.00
65 ≤	118	1.05	0.69–1.62
Gender				0.16
Female	83	1.00
Male	170	1.34	0.88–2.15
Tumor size (mm)				0.84
< 65	135	1.00
65 ≤	118	1.04	0.70–1.57
Histological type				0.82
Undifferentiated	140	1.00
Differentiated	113	1.05	070–1.58
Pathological Stage				<0.001			<0.001
II	103	1.00			1.00
III	150	2.33	1.47–3.71		2.44	1.50–3.95
Vascular invasion				0.28
v0	73	1.00
v1–3	180	1.29	0.81–2.03
Lymphatic invasion				0.008			0.011
ly0	81	1.00			1.00
ly1–3	172	1.91	1.18–3.08		1.94	1.16–3.22
Adjuvant therapy				0.49			0.018
Yes	146	1.00			1.00
No	107	1.15	0.77–1.64		1.68	1.09–2.59