Figure 4.

Exploration of the atomic novelty search on the Plakortis halichondrioides extract (IM06–19) identifies gracilioether L. a) Structure of gracilioether L along with the top peaks C1-C4 from ¹H-¹³C HSQC spectrum in CD₃OD. b) Profiled ¹H-¹³C HSQC of the IM06–19 extract. c) Profiled ¹H-¹³C HSQC of isolated gracilioether L. d)-g) Graphical rendering of the Euclidian distance evaluations between peaks C1-C4 observed in the spectrum of purified gracilioether L (red points) and its closest peaks in the database (black points). Supporting Fig. S2 provides chemical structures of closest database peaks to C1-C4. The stereochemistry at C6 and C10 was not determined.