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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: JACC Heart Fail. 2019 Aug 7;8(1):70–80. doi: 10.1016/j.jchf.2019.07.005

Table 4a.

Soluble Neprilysin (ng/mL) Levels in HFpEF Patients Compared to Community Based Controls without HFpEF

Adjustment HF adj mean (CI) N=242 Non-HF adj mean (CI) N=891 p-value
None 3.5 (2.5, 4.8) 8.5 (7.2, 10.0) <0.001
Smoking hx 3.6 (2.6, 5.0) 8.4 (7.1, 9.8) <0.001
Age, Gender, BMI, Smoking hx 4.0 (2.7, 5.9) 8.2 (6.8, 9.7) 0.002
Age, Gender, BMI, Smoking hx, Ace-I 4.3 (2.8, 6.4) 8.1 (6.7, 9.8) 0.009
Age, Gender, BMI, Smoking hx, Ace-I, Hyperlipidemia 4.5 (2.9, 7.0) 8.0 (6.6, 9.7) 0.04
Age, Gender, BMI, Smoking hx, HTN 4.2 (2.8, 6.4) 8.0 (6.7, 9.6) 0.01