Table 1.
Characteristics of the MESA Angiogenesis Cohort
| n=1,361 | |
|---|---|
| Mean Endothelin-1 (pg/mL) | 51.3 ± 9.7 |
| Endothelin-1 range (pg/mL) | 34.6 − 189.1 |
| Age (years) | 61 ± 10 |
| Female (%) | 52 |
| Race (%) | |
| White | 40 |
| Chinese | 12 |
| African-American | 27 |
| Hispanic | 21 |
| Height (cm) | 166 ± 10 |
| Weight (kg) | 77 ± 16 |
| Body mass index (kg/m2) | 28 ± 5 |
| Educational attainment (%) | |
| No high school degree | 16 |
| High school degree | 19 |
| Some college or certificate | 28 |
| Bachelor’s Degree | 17 |
| Higher than bachelor’s degree | 20 |
| Insurance Status (%) | |
| No insurance | 7 |
| Medicare | 33 |
| Private insurance | 76 |
| Cigarette smoking status (%) | |
| Never | 53 |
| Former | 36 |
| Current | 11 |
| Pack-years | 10 ± 21 |
| Metabolic Syndrome (%) | 33 |
| Hypertension (%) | 43 |
| Systolic blood pressure (mmHg) | 125 ± 21 |
| Diabetes mellitus (%) | 13 |
| Glucose (mg/dL) | 97 ± 31 |
| Cholesterol (mg/dL) | 194 ± 33 |
| NT-ProBNP (pg/mL) | 93 ± 147 |
| Medications (%) | |
| NSAIDs | 42 |
| Beta-blockers | 9 |
| ACE-inhibitors/ARBs | 17 |
| Any diuretic | 12 |
Data presented as mean ± standard deviation or percentage as appropriate Abbreviations: pg=picogram, mL=milliliter, cm=centimeters, kg=kilograms, m2=meters squared, mmHg=millimeters of mercury, mg=milligram, dL=deciliter, NT-ProBNP=amino-terminal fragment of pro-B-type natriuretic peptide NSAIDs=non-steroidal anti-inflammatory medications, ACE-inhibitors= angiotensin converting enzyme inhibitors, ARBs=angiotensin II receptor blockers