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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Mol Cancer Res. 2019 Oct 16;18(1):166–178. doi: 10.1158/1541-7786.MCR-19-0204

Figure 1. Lung targeted PRMT6 expression accelerates cell proliferation.

Figure 1.

A. TLA coverage and analysis plots. Left panel represents the sequence coverage: mouse chromosomes 1 through X are arranged on the Y-axis and X-axis represents chromosomal position. While, right panel displays the graphical representation of transgene integration site and structural changes. B. Tissue lysates from the lungs of PRMT6Tg; Sftpc-Cretm and PRMT6Tg control mice after tamoxifen treatment were subjected to immunoblotting with anti-PRMT6 antibodies that detects both human and mouse PRMT6 isoforms. C, D. 40 weeks after tamoxifen administration to induce PRMT6 expression, lung sections were subjected to H&E staining (C, scale bar: 100 μM) and Indirect immunofluorescence with anti-ki67 antibodies (D, scale bar: 200 μM). Upper panel represents the quantification of ki67 staining, while representative images were displayed in the lower panel. **, p< 0.01; versus PRMT6Tg control.