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. 2020 Jan 3;19:1. doi: 10.1186/s12904-019-0499-1

Table 5.

Two-way mixed MANCOVA (multivariate) and two-way mixed ANCOVA (univariate) with confounders as covariates

Multivariate Univariate
Anxiety & depression Anxiety Depression
Covariates at T1 and T2 Test statistics Sig. 2-tailed Test statistics Sig. 2-tailed Effect size Test statistics Sig. 2-tailed Effect size
Effect F(2, 12) p F(1, 13) p r F(1, 13) p r
Pain Group 0.23 0.79 0.49 0.50 0.19 0.32 0.58 0.15
Time 4.90 0.028* 8.79 0.011* 0.64 1.73 0.21 0.34
Group x time 5.31 0.022* 9.15 0.010* 0.64 1.54 0.24 0.33
AEDL Group 0.21 0.81 0.09 0.77 0.08 0.08 0.78 0.08
Time 3.44 0.066+ 7.20 0.019* 0.60 2.61 0.13 0.41
Group x time 5.32 0.022* 9.48 0.009* 0.65 1.60 0.23 0.33
Psychooncological treatment (minutes) Group 0.67 0.53 1.45 0.25 0.32 0.48 0.50 0.19
Time 7.77 0.007* 16.76 0.001* 0.75 4.60 0.051+ 0.51
Group x time 4.27 0.040* 8.22 0.013* 0.62 0.68 0.43 0.22
Days with antidepressants Group 0.10 0.91 0.22 0.65 0.13 0.10 0.76 0.09
Time 2.43 0.13 4.48 0.054+ 0.51 0.61 0.45 0.21
Group x time 4.95 0.027* 9.39 0.009* 0.65 1.51 0.24 0.32
Palliative care treatment (days) Group 0.15 0.86 0.32 0.58 0.15 0.18 0.68 0.12
Time 2.66 0.11 4.71 0.049* 0.52 4.95 0.044* 0.53
Group x time 4.41 0.037* 6.89 0.021* 0.59 0.33 0.58 0.16

*p: statistical significance p < 0.05

+p: trend to statistical significance: 0.05 < p < 0.10