Table 1.

Increased inflammatory mediator levels 24 h after experimental meningitis induction in the PFC and hippocampus. The results are expressed as the mean ± SEM for n = 5–6 rats

Cytokines (pg/μg)	PFC—24 h		Hippocampus—24 h
	Control	Meningitis	Control	Meningitis
IL-1a	0.018 ± 0.001	0.711 ± 0.222*	0.014 ± 0.001	0.199 ± 0.020*
IL-1β	0.165 ± 0.009	1.569 ± 0.256*	0.107 ± 0.008	0.267 ± 0.027*
IL-4	0.009 ± 0.001	0.007 ± 0.001	0.005 ± 0.0004	0.005 ± 0.0009
IL-5	0.052 ± 0.003	0.046 ± 0.009	0.034 ± 0.002	0.315 ± 0.003
IL-6	0.077 ± 0.005	0.984 ± 0.030*	0.059 ± 0.005	0.447 ± 0.050*
IL-7	0.010 ± 0.0007	0.007 ± 0.0008*	0.003 ± 0.0002	0.002 ± 0.0008
IL-10	0.033 ± 0.004	0.019 ± 0.001*	0.022 ± 0.001	0.023 ± 0.001
IL-12	0.013 ± 0.001	0.006 ± 0.008	0.009 ± 0.001	0.009 ± 0.0008
IL-13	0.027 ± 0.001	0.012 ± 0.0008*	0.012 ± 0.0008	0.011 ± 0.001
IL-17	0.021 ± 0.002	0.041 ± 0.001*	0.011 ± 0.0002	0.014 ± 0.001
IL-18	0.037 ± 0.003	0.050 ± 0.006	0.031 ± 0.002	0.043 ± 0.003*
TNF-α	0.054 ± 0.004	0.312 ± 0.029*	0.041 ± 0.005	0.059 ± 0.003*
INF-γ	0.021 ± 0.002	0.070 ± 0.006*	0.023 ± 0.002	0.069 ± 0.006*

*P < 0.05 compared to controls