Table 2.

Increased inflammatory mediator levels 10 days after experimental meningitis induction in the PFC and hippocampus. The results are expressed as the mean ± SEM for n = 5–6 rats

Cytokines (pg/μg)	PFC—10 days		Hippocampus—10 days
	Control	Meningitis	Control	Meningitis
IL-1a	0.1083 ± 0.012	0.133 ± 0.016	0.082 ± 0.013	0.096 ± 0.014
IL-1β	0.347 ± 0.029	0.316 ± 0.026	0.212 ± 0.015	0.175 ± 0.009
IL-4	0.009 ± 0.001	0.006 ± 0.001	0.010 ± 0.001	0.022 ± 0.002*
IL-6	0.423 ± 0.048	0.480 ± 0.067	0.198 ± 0.031	0.199 ± 0.025
IL-10	0.084 ± 0.006	0.110 ± 0.016	0.029 ± 0.004	0.031 ± 0.004
IL-12	0.192 ± 0.022	0.085 ± 0.011*	0.08 ± 0.013	0.086 ± 0.009
IL-17	0.088 ± 0.008	0.043 ± 0.008*	0.040 ± 0.006	0.019 ± 0.003*
IL-18	0.043 ± 0.004	0.039 ± 0.004	0.077 ± 0.011	0.073 ± 0.004
TNF-α	0.022 ± 0.001	0.032 ± 0.002*	0.019 ± 0.002	0.019 ± 0.001
INF-γ	0.093 ± 0.007	0.101 ± 0.006	0.082 ± 0.008	0.074 ± 0.004

*P < 0.05 compared to controls