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. 2020 Jan 3;10:1. doi: 10.1186/s13578-019-0370-3

Table 5.

miRNAs in clinical trials

miRNA Drug name Disease
miR-34 MRX34 Multiple cancers
miR-92

MRG110

MGN-6114

Heart failure/wound healing
miR-16 mesomiR-1 Mesothelioma, lung cancer
miR-122

Miravirsen

RG101

Hepatitis C virus
miR-29

MRG201

MGN4220

Keloid, fibrous scar tissue formation
miR-21 RG012 Alport syndrome
miR-155 Cobomarsen (MRG-106) T-cell lymphoma/mycosis fungoides
miR-143/145 MGN2677 Vascular disease
miR-451 MGN-4893 Polycythemia vera
miR-378 MGN5804 Cardiometabolic disease
miR-15/miR-195 MGN-1374 Post-myocardial infarction remodelling
miR-208 MGN9103 Heart failure