Fig. 3.

PROs by ASAS40 response at Week 104. The response status was defined at Week 104, and only patients with data available at that week were included. Data shown are the adjusted mean change from Baseline (95% CI) except plots for WPAI data, which show adjusted mean change from Baseline in the percentage of patients (95% CI). The numbers of patients with available change from Baseline data are shown in or near the columns. Significant difference in change in PRO adjusted mean from Baseline between ASAS40 responders and non-responders is indicated (**p < 0.01; ***p < 0.001). ASDAS, Ankylosing Spondylitis Disease Activity Score; ASQoL, ankylosing spondylitis quality of life; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; CFB, change from Baseline; CI, confidence interval; EQ-5D, EuroQol-5 Dimensions; MCS, mental component summary; MFI, Multidimensional Fatigue Inventory; PCS, physical component summary; PRO, patient-reported outcome; SF-36, 36-item short form health survey; VAS, visual analog scale; WPAI, Work Productivity and Activity Index