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. 2019 Dec 31;14:10147–10164. doi: 10.2147/IJN.S234393

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© 2019 Torre et al.

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Gene expression analysis of J774a1 macrophage cells incubated into Transwell^® inserts with ordered mesoporous carbon C3 doped with or without Ag 2wt% and Ag 10wt%. All three C3 nanomatrices (pristine and silver-doped) induced enhanced IL-6 and TNF-α expression, compared to polystyrene, whereas an increase of IL-1β levels is only seen in C3Ag10-stimulated J774a.1 macrophages, at 48 hrs incubation time. Data are expressed as mean (SD). P values ≤0.05 were considered to be statistically significant (*p≤0.05; **p≤0.01; ***p≤0.001).