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. 2019 Dec 31;12:11679–11690. doi: 10.2147/OTT.S231630

Table 2.

Clinical Significance of SNHG16 in Diverse Cancers

Cancer Type Overexpression of SNHG16 and Clinical Features References
Non-small cell cancer Tumor size, TNM stage, lymph node metastasis, shorter DFS and OS [32]
Hepatocellular carcinoma TNM stage, metastasis [29]
Tumor size, TNM stage, ALT (U/L) [14]
Shorter DFS and OS, multiple tumors, macro vascular invasion [26]
Shorter DFS and OS [28]
Lymph node involvement, TNM stage [27]
Tumor size, TNM stage, vascular invasion [25]
Tumor size, TNM stage, metastasis, portal vein tumor thrombus (PVTT) [30]
Cervical cancer Tumor size, FIGO stage, lymph node metastasis, poor differentiation [34,35]
Osteosarcoma Tumor size, TNM stage, metastasis, shorter OS [39]
Tumor size, TNM stage, distance, metastasis, shorter OS [41]
Papillary thyroid cancer TNM stage, lymph nodes, [42]
Glioma Tumor size, WHO stage, shorter OS and PFS, [51]
Colorectal cancer Metastasis, lymph node metastasis [13]
Ovarian cancer Clinical stage, distance metastasis, shorter OS [53]
Bladder cancer Historical grade, tumor stage, lymph node metastasis [35]
Metastasis, lymph nodes, pathological stage [34]
Gastric cancer Lymph node metastasis, invasive depth, TNM stage [67]
Pancreatic cancer Tumor size, TNM stage, lymph node metastasis, differentiation [41]