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. Author manuscript; available in PMC: 2020 Jan 4.
Published in final edited form as: Nature. 2019 Jun 5;570(7760):236–240. doi: 10.1038/s41586-019-1251-y

Extended Data Figure 7. An admixture graph connecting various modern meta-populations and ancient populations or individuals.

Extended Data Figure 7.

As derived in Supplementary Information section 10, the graph features a simplified three-component model for Europeans as previously suggested36 and two gene flows from a European lineage related to the ancient Siberian genome MA-135 into Native Americans and Siberians. The topology within the proto-Paleo-Eskimo clade was obtained by cycling through dozens of trees with all possible topologies of branches and admixture edges and selecting the one with the highest support and no 0-length edges within the proto-Paleo-Eskimo clade.