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. 2019 Nov 12;55(1):113–122. doi: 10.1007/s00535-019-01642-1

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Waterfall plot showing maximum changes in tumor size in the Japanese patients by lenvatinib and sorafenib. Target regions of tumors were examined in the individual patients and assessed for tumor size by local investigators (a, b) and by masked independent imaging review (c, d) according to mRECIST. The waterfall plot represents maximum changes in tumor size of each patient receiving lenvatinib (a, c) and sorafenib (b, d)