Table 3.
Clinicopathological features of adjuvant and non-adjuvant patients
| Total | Non-adjuvant (N = 102) | Adjuvant (N = 432) | P value |
|---|---|---|---|
| Age (median, IQR; years) | 70.5 (60–80) | 64 (55–71) | < 0.001 |
| Gender | |||
| Male | 58 (56.9%) | 236 (54.6%) | 0.766 |
| Female | 44 (43.1%) | 196 (45.4%) | |
| Location | |||
| Esophagus | 5 (4.9%) | 2 (0.5%) | 0.005 |
| Stomach | 56 (54.9%) | 262 (60.6%) | |
| Small intestine | 30 (29.4%) | 133 (30.8%) | |
| Colon and rectum | 9 (8.8%) | 23 (5.3%) | |
| Others | 2 (2.0%) | 12 (2.8%) | |
| PS | |||
| 0 | 77 (75.5%) | 370 (85.6%) | 0.004 |
| 1 | 20 (19.6%) | 56 (13.0%) | |
| 2 | 3 (2.9%) | 1 (0.2%) | |
| 3 | 2 (2.0%) | 1 (0.2%) | |
| Neoadjuvant | |||
| (−) | 95 (93.1%) | 380 (88.0%) | 0.186 |
| (+) | 7 (6.9%) | 52 (12.0%) | |
| Surgery | |||
| Open | 71 (69.6%) | 316 (73.1%) | 0.551 |
| Laparoscopic | 31 (30.4%) | 116 (26.9%) | |
| Curability of surgery | |||
| R0 | 100 (98.0%) | 417 (96.5%) | 0.639 |
| R1 | 2 (2.0%) | 15 (3.5%) | |
| Tumor size (median, IQR: cm) | |||
| 6.5 (5.1–10.0) | 7.7 (5.5–12.0) | 0.035 | |
| Unavailable | 0 | 1 | |
| Mitosis (median, IQR:/50HPF) at local | |||
| 8 (4–17) | 11 (5–25) | 0.009 | |
| Unavailable | 6 | 31 | |
| Tumor rupture | |||
| No | 94 (92.2%) | 365 (84.5%) | 0.042 |
| Yes | 6 (5.9%) | 60 (13.9%) | |
| Unavailable | 2 (2.0%) | 7 (1.6%) | |
| Histological types | |||
| Spindle | 86 (84.3%) | 360 (83.3%) | 0.343 |
| Epithelioid | 1 (1.0%) | 16 (3.7%) | |
| Mixed | 10 (9.8%) | 36 (8.3%) | |
| Unavailable | 5 (4.9%) | 20 (4.6%) | |
| Genotyping | |||
| KIT | 84 (82.4%) | 372 (86.1%) | 0.829 |
| PDGFRA | 4 (3.9%) | 14 (3.2%) | |
| Wild type | 8 (7.8%) | 29 (6.7%) | |
| Unavailable | 10 (9.8%) | 31 (7.2%) | |