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. 2019 Oct 28;21(1):109–123. doi: 10.1007/s10522-019-09846-x

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — Chronological lifespan of the haploid wild-type yeast strain BY4741 (a) and isogenic mutant strains sod1Δ (b), sod2Δ (c), rad52Δ (d) treated with curcumin. Survival was determine by propidium iodide staining. Statistical significance was assessed using ANOVA and the Dunnett’s post hoc test (**p < 0.01, ***p < 0.001) compared to the control (untreated). Bars indicate SD