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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Clin Cancer Res. 2019 Nov 6;26(1):71–81. doi: 10.1158/1078-0432.CCR-19-2078

Figure 2. IV delivered pelareorep replicates in tumor tissues, promoting T cell recruitment to the TME.

Figure 2.

Representative histological analysis from patient #002. (A-C) Micrographs for reoviral RNA in blue (A), reoviral caspid protein in brown (B), and a merged image with both viral RNA (blue) and protein (red) (C). Analysis or pre- and post- PD-L1 (D, D′), CD8 (E, E′), and Caspase 3 (F, F′) expression in the TME.