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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Clin Cancer Res. 2019 Nov 6;26(1):71–81. doi: 10.1158/1078-0432.CCR-19-2078

Table 2.

Pre and post treatment histology analysis.

Patient
Number
Timepoint Viral
RNA*
(SD)
Viral
protein*
(SD)
Caspase 3*
(SD)
CD8*
(SD)
PD L1**
(SD)
IDO 1*
(SD)
002 Pre 0 0 6.1 (2.8) 16.9 (6.6) 31.3 (6.6) 37.5 (10.9)
Post 65.7% (8.3) 4.3% (3.1) 11.1 (5.5) 37.0 (11.9) 25.6 (9.6) 27.7 (13.9)
004 Pre 0 0 - 61.1 (13.3) 43.1 (7.9) -
Post 54.9% (7.9) 2.3% (0.9) 11.2 (4.4) 153.9 (11.3) 42.9 (8.8) 13.9 (3.9)
005 Pre 0 0 - 11.1 (4.4) 24.5 (4.4) -
Post - - - - - -
006 Pre 0 0 5.4 (2.3) 1.5 (1.2) 2.4 (0.8) 1.1 (0.5)
Post 78.4% (7.4) 1.6 % (1.0) 26.6 (8.3) 2.0 (1.1) 4.4 (1.1) 4.4 (1.4)
007 Pre 0 0 1.9 (1.6) 11.1 (3.9) 10.1 (3.9) 2.9 (1.6)
Post 75.9% (6.6) 0.5% (0.4) 3.9 (2.2) 15.3 (5.5) 16.9 (4.4) 4.7 (1.8)
010 Pre 0 0 2.0 (0.9) 13.3 (3.4) 13.1 (3.9) 2.9 (1.6)
Post - - - - - -
*

number of positive cells per field (20X);

**

% of positive cells;

SD, Standard deviation;

- No tumor, fibrosis