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Table 3. General recommendations for screening and follow-up of kidney disease in patients with HIV infection.

Assessment At HIV infection diagnosis and initiation of ART Follow-up
Risk assessment + Every visit*, as needed**
Lifestyle optimization + Every visit
Urine analysis + Annually
Proteinuria (dipstick) +*** Annually
Serum creatinine + Annually or more frequently, if indicated
Estimated GFR (CKD-EPI formula) + 3-12 months

ART – antiretroviral therapy; CKD – chronic kidney disease; GRF – glomerular filtration rate.

*

A visit is defined as a regular consult with an ID specialist, which may occur every 6 months, or sooner if medically-indicated.

**

CKD risk factors and treatment with ARV agent with potential nephrotoxicity; the D:A:D score recommended for renal risk assessment (medium risk 0-4, high risk >5).

***

If dipstick test for proteinuria is positive, recommend urinary protein/creatinine ratio.