Table 3.

Population and Baseline Characteristics

	Current Standard of Care (N = 50)	Strict Glucose Control (N = 50)	P-Value
Patient Demographics
Age	55.0 [50.0 to 59.0]	54.0 [48.0 to 57.0]	0.201
Race			0.580
White	41 (82.0)	41 (82.0)
African American	4 (8.0)	5 (10.0)
Asian	1 (2.0)	0 (0.0)
Other	4 (8.0)	4 (8.0)
WHO BMI Classification			0.415
Underweight	0 (0.0)	0 (0.0)
Normal	12 (24.5)	10 (20.0)
Overweight	18 (36.7)	14 (28.0)
Obese	19 (38.8)	26 (52.0)
Female Sex	14 (28.0)	12 (24.0)	0.648
Pre-Existing Conditions
Diabetes	16 (32.0)	13 (26.0)	0.509
CAD	4 (8.0)	4 (8.0)	0.999
MELD Score	20.5 [15.0 to 23.0]	19.5 [12.5 to 25.5]	0.744
Cause of Liver Disease¹
Alagille’s Syndrome	0 (0.0)	2 (4.0)	0.495
Alpha-1 Antitrypsin Deficiency	4 (8.0)	0 (0.0)	0.118
Hepatocellular Carcinoma (non-Fibrolamellar)	13 (26.0)	19 (38.0)	0.198
Alcohol-related Cirrhosis	18 (36.0)	12 (24.0)	0.190
Cryptogenic Cirrhosis	4 (8.0)	5 (10.0)	0.999
Primary Biliary Cirrhosis	2 (4.0)	1 (2.0)	0.999
Secondary Biliary Cirrhosis	1 (2.0)	0 (0.0)	0.999
Cystic Fibrosis	1 (2.0)	0 (0.0)	0.999
Hemochromatosis	1 (2.0)	0 (0.0)	0.999
Hepatitis C, Chronic	18 (36.0)	18 (36.0)	0.999
Hepatitis, Chronic Active	2 (4.0)	3 (6.0)	0.999
Hepatic Failure (Idiopathic)	1 (2.0)	0 (0.0)	0.999
HCC	1 (2.0)	1 (2.0)	0.999
Hypertensive Nephrosclerosis	1 (2.0)	0 (0.0)	0.999
Polycystic Liver Disease	1 (2.0)	0 (0.0)	0.999
Non-Alcoholic Steatohepatitis	2 (4.0)	4 (8.0)	0.678
Primary Sclerosing Cholangitis	5 (10.0)	8 (16.0)	0.554
Unknown	1 (2.0)	1 (2.0)	0.999
Wilson’s Disease	0 (0.0)	1 (2.0)	0.999

¹Cause of liver disease is not mutually exclusive. Data are presented as frequency (%) or median [25th percentile to 75th percentile], as appropriate