Table 3. Evaluation of cytotoxic and anti-HSV-1 activity of ethyl acetate extract of supernatant from P. rubra and V. salarius.

Extract of Bacteria species	CC50 (µg/ml)	EC50 (µg/ml)
Pseudoalteromonas rubra	75	–
Virgibacillus salarius	>1000	–
Acyclovir	>5	0.5

Notes:

(–), no cytotoxic effect.

CC_50, the 50% cytotoxic concentration of extract in Vero cells (µg/ml).

EC_50, concentration of compound in µg/ml producing 50% inhibition of virus-induced cytopathic effect.