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. 2019 Dec 14;2019:5892913. doi: 10.1155/2019/5892913

Table 2.

Mycobacterium abscessus subsp. abscessus: in vitro antibiotic susceptibility and genome sequencing results. Breakpoints according to CLSI [19].

Antibiotics 07.02.2018 08.07.2018 10.01.2018 10.02.2018
4-day reading (mg/L) 4-day reading (mg/L) 14-day reading (mg/L) ∗∗14-day reading (mg/L)
23s-wild type-macrolide constitutive resistance not detected
16s-wild type-susceptible to amikacin erm(41)-wild type-macrolide-inducible resistance detected
Amikacin 3 (S) 16 (S)
Tigecyclin 0.5 (S) 0.75 (S)
Clarithromycin 0.5 (S) 1.5 (S) 4 (R) 4 (R)
Imipenem 4 (S) 32 (R)
Linezolid 8 (R) >256 (R)
Azitromycin 128 (R)
Moxifloxacin >32 (R)
Gentamycin 12 (R)

E-test, Middlebrook 7H-11 agar; ∗∗broth microdilution testing, Middlebrook 7H-9 broth.