Figure 4.
Modulation of MALAT1, TOX, and miR-181b regulated the expression of TNF-α, ROS production, and NADPH oxidase activity. (a–c) TNF-α protein expression was determined after treating with MALAT1 shRNA, TOX siRNA, and miR-181b mimic, together with ROS production (d–f) and NADPH oxidase activity (g–i). ∗P < 0.05 versus the control group; #P < 0.05 versus the oxLDL control group.