2.
与药敏患者相比单耐药异烟肼患者血清代谢组学差异指标筛选结果
Screening results of serum metabonomics difference indexes in patients with single drug resistance to INH compared with patients with drug sensitivity
| Metabolite | M/z | RT | FC | P |
| Acetylagmatine | 195.1220 | 21.7092 | 13.0985 | 0.0086 |
| Aminopentol | 406.3535 | 21.8668 | 9.9559 | 0.0389 |
| N-stearoyl glutamic acid | 414.3214 | 20.1007 | 7.7795 | 0.0110 |
| 5-Pentacosyl-1, 3-benzenediol | 483.4135 | 21.8005 | 6.8282 | 0.0021 |
| PAF C-16 | 524.3712 | 8.2182 | 5.3187 | 0.0001 |
| Fasciculic acid A | 621.4396 | 4.6199 | 5.2786 | 0.0338 |
| PE(18:0/0:0) | 482.3239 | 8.4746 | 5.2059 | 0.0000 |
| 25-hydroxy-cholesterol (d3) | 444.3320 | 17.5218 | 4.1436 | 0.0166 |
| PAF C18 | 550.3865 | 8.7556 | 4.1261 | 0.0000 |
| 25-dihydroxy-26, 27-dimethyl-20, 21-didehydro-23-oxavitamin D3 | 447.3443 | 22.4050 | 4.0969 | 0.0106 |
| (Z)-22-Hentriacontene-2, 4-dione | 485.4308 | 21.6702 | 3.8258 | 0.0001 |
| 5S-HETE di-endoperoxide | 403.2323 | 4.0293 | 3.6354 | 0.0439 |
| Eicosanoyl-EA | 356.3519 | 4.8929 | 3.6000 | 0.0243 |
| Penaresidin A | 330.2998 | 2.3504 | 3.3876 | 0.0396 |
| 2-Amino-3-methyl-1-butanol | 104.1070 | 8.2203 | 3.3856 | 0.0000 |
| N, N-dimethyl-Safingol | 330.3365 | 10.6213 | 3.3439 | 0.0198 |
| 3-Methylbutanamine | 88.1120 | 21.7168 | 3.3431 | 0.0010 |
| Phthalic acid Mono-2-ethylhexyl Ester | 279.1588 | 5.8530 | 3.2441 | 0.0022 |
| N-Methyldioctylamine | 256.2998 | 3.5361 | 3.0819 | 0.0104 |
| DL-Cerebronic acid | 407.3526 | 22.0390 | 3.0401 | 0.0243 |
| Loroxanthin ester/Loroxanthin dodecenoate | 803.5432 | 12.6418 | 0.4028 | 0.0000 |
| B-Octylglucoside | 315.1774 | 14.0229 | 0.3767 | 0.0007 |
| PC(14:0/22:6 (4Z, 7Z, 10Z, 13Z, 16Z, 19Z)) | 816.4949 | 12.6361 | 0.3701 | 0.0002 |
| 2, 3-DINOR-THROMBOXANE B2 | 343.2108 | 18.9415 | 0.3611 | 0.0294 |
| 2, 3-dinor, 6-keto-PGF1 & alpha | 365.1943 | 10.6038 | 0.3524 | 0.0065 |
| (3R)-3-isopropenyl-6-oxoheptanoic acid | 185.1171 | 17.5022 | 0.3440 | 0.0496 |
| isopropyl ester | 429.2400 | 12.6400 | 0.3271 | 0.0001 |
| Linolenyl oleate | 529.5018 | 18.6844 | 0.3255 | 0.0005 |
| PE(16:1(9Z)/P-18:1(11Z)) | 722.5045 | 22.1278 | 0.2939 | 0.0424 |
| Arachidyl carnitine | 478.3910 | 12.6401 | 0.2840 | 0.0000 |
| Kamahine C | 269.1384 | 13.2653 | 0.2656 | 0.0402 |
| DG(18:2(9Z, 12Z)/0:0/18:2(9Z, 12Z)) (d5) | 634.4526 | 14.3205 | 0.2655 | 0.0355 |
| Heneicosanedioic acid | 357.2977 | 11.9339 | 0.2560 | 0.0212 |
| Heptadecanoyl carnitine | 436.3425 | 12.6234 | 0.2367 | 0.0482 |
| Demethylimipramine | 267.1853 | 18.7583 | 0.2315 | 0.0491 |
| 9, 15-dioxo-11R-hydroxy-2, 3, 4, 5-tetranor-prostan-1, 20-dioic acid | 329.1594 | 9.0095 | 0.2174 | 0.0208 |
| (3R)-3-isopropenyl-6-oxoheptanoic acid | 185.1171 | 18.9333 | 0.2068 | 0.0041 |
| 2, 4-Dideoxy-2-octylpentaric acid | 283.1512 | 17.4527 | 0.1633 | 0.0433 |
| Tetracosanyl oleate | 629.5688 | 20.0818 | 0.0837 | 0.0100 |