4.
与药敏患者相比耐多药患者血清代谢组学差异指标筛选结果
Screening results of serum metabonomics difference indexes in patients with single drug resistance to MDR compared with patients with drug sensitivity
| Metabolite | M/z | RT | FC | P |
| Trimethylamine | 60.0805 | 22.5874 | 8.1845 | 0.0094 |
| Penaresidin A | 330.2998 | 2.3504 | 6.4056 | 0.0017 |
| Eicosanoyl-EA | 356.3519 | 4.8929 | 6.0852 | 0.0009 |
| AV-Ceramide | 678.4792 | 18.4792 | 4.0377 | 0.0111 |
| PAF C-16 | 524.3712 | 8.2182 | 3.7202 | 0.0002 |
| 25-hydroxy-cholesterol(d3) | 444.3320 | 17.5218 | 3.7082 | 0.0160 |
| N-Cyclohexanecarbonylpentadecylamine | 338.3416 | 17.5992 | 3.5865 | 0.0330 |
| 25-dihydroxy-26, 27-dimethyl-20, 21-didehydro-23-oxavitamin D3 | 447.3443 | 22.4050 | 3.4404 | 0.0238 |
| PAF C18:1 | 550.3865 | 8.7556 | 3.3867 | 0.0000 |
| 2-Amino-3-methyl-1-butanol | 104.1070 | 8.2203 | 2.9023 | 0.0000 |
| Ala His Pro Thr | 425.2145 | 4.9616 | 2.8547 | 0.0191 |
| Artomunoxanthentrione epoxide | 485.1206 | 13.4043 | 2.8425 | 0.0001 |
| 13, 14-dihydro-16, 16-difluoro Prostaglandin D2 | 391.2297 | 8.3736 | 2.7140 | 0.0291 |
| Phthalic acid Mono-2-ethylhexyl Ester | 279.1587 | 5.4766 | 2.6058 | 0.0005 |
| Magnoshinin | 437.1935 | 2.8333 | 2.5956 | 0.0000 |
| N-stearoyl glutamic acid | 414.3214 | 20.1007 | 2.5709 | 0.0182 |
| Quinapril hydrochloride | 475.2004 | 7.6535 | 2.4944 | 0.0000 |
| Cys Phe Asn Asn | 497.1823 | 7.6559 | 2.4848 | 0.0005 |
| Ala Cys Ile Trp | 492.2269 | 7.6491 | 2.4624 | 0.0000 |
| Tolvaptan | 487.1183 | 14.6959 | 2.4465 | 0.0080 |
| Arachidyl carnitine | 478.3910 | 12.6401 | 0.2918 | 0.0000 |
| Glycinoprenol-9 | 659.6155 | 20.5882 | 0.2794 | 0.0003 |
| Dodecanoylcarnitine | 344.2794 | 9.5484 | 0.2711 | 0.0052 |
| Soyasapogenol B 3-O-D-glucuronide | 673.3740 | 17.3500 | 0.2585 | 0.0325 |
| Hexacosanedioic acid | 449.3599 | 10.6216 | 0.2538 | 0.0081 |
| Dihydroshikonofuran | 261.1484 | 12.6440 | 0.2163 | 0.0000 |
| Ala Ser Arg | 355.1700 | 22.5095 | 0.2074 | 0.0151 |
| 3α-Hydroxy-6-oxo-5β-cholan-24-oic Acid | 391.2844 | 18.4706 | 0.1980 | 0.0020 |
| Voacamine | 727.3826 | 15.0403 | 0.1908 | 0.0067 |
| D-Glucosyldihydrosphingosine | 502.3165 | 8.4657 | 0.1862 | 0.0365 |
| 9, 15-dioxo-11R-hydroxy-2, 3, 4, 5-tetranor-prostan-1, 20-dioic acid | 329.1594 | 7.5628 | 0.1850 | 0.0271 |
| PG(18:3(6Z, 9Z, 12Z)/0:0) | 507.2717 | 7.5320 | 0.1822 | 0.0158 |
| Thr Ala Arg | 347.2040 | 21.7912 | 0.1055 | 0.0213 |
| PC(P-16:0/2:0) | 522.3557 | 5.3494 | 0.1010 | 0.0004 |
| Cer(d18:0/12:0) | 484.4724 | 12.9413 | 0.0813 | 0.0012 |
| Verazine | 398.3454 | 13.0757 | 0.0087 | 0.0016 |