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Criteria for histopathological scoring of the colon tissue of the mice
| Severity of inflammation | Depth of lesion | Crypt destruction | Lesion range | Score |
| Normal tissue | No lesion | No damage | No lesion | 0 |
| Mild inflammation | Lesions invade lamina propria | Basal 1/3 recess is destroyed | 1%-25% | 1 |
| Severe inflammation | L esions invade submucosa | Basal 2/3 recess is destroyed | 26%-50% | 2 |
| L esions invade the mucosa | Only superficial epithelium is intact | 51 %-75% | 3 | |
| All crypts and epithelium are destroyed | 76%-100% | 4 |
