2.
肝癌各种影响因素对患者无瘤生存率的影响
Influence of different factors on tumor-free survival of HCC patients
| Variable | n | Univariate analysis | Multivariate analysis model | |||
| HR (95% CI) | P | HR (95% CI) | P | |||
| HR: Hazard ratio; CI: Confidence interval. | ||||||
| Gender | 1.365 (0.884-2.674) | 0.669 | - | - | ||
| Male | 89 | - | - | - | - | |
| Female | 86 | - | - | - | - | |
| Age (year) | 0.694 (0.674-1.864) | 0.396 | - | - | ||
| < 50 | 83 | - | - | - | - | |
| ≥50 | 92 | - | - | - | - | |
| AFP (ng/mL) | 1.081 (0.559-1.836) | 0.763 | - | - | ||
| ≤20 | 64 | - | - | - | - | |
| > 20 | 111 | - | - | - | - | |
| HBsAg | 1.264 (0.636-2.008) | 0.457 | - | - | ||
| Positive | 120 | - | - | - | - | |
| Negative | 55 | - | - | - | - | |
| Liver Cirrhosis | 0.570 (0.983-2.647) | 0.364 | - | - | ||
| Presence | 113 | - | - | - | - | |
| Absence | 62 | - | - | - | - | |
| TNM stage | 0.863 (0.578-1.867) | 0.630 | - | - | ||
| Ⅰ/Ⅱ | 89 | - | - | - | - | |
| Ⅲ/Ⅳ | 86 | - | - | - | - | |
| Tumor size (cm) | 1.360 (0.492-1.650) | 0.035 | 1.089 (1.075-2.637) | 0.043 | ||
| ≤5 | 77 | - | - | - | - | |
| > 5 | 98 | - | - | - | - | |
| Intrahepatic metastasis | 2.962 (1.064-3.478) | 0.016 | 2.551 (0.482-3.664) | 0.021 | ||
| Presence | 99 | - | - | - | - | |
| Absence | 76 | - | - | - | - | |
| Vascular invasion | 1.506 (0.895-2.647) | 0.007 | 2.907 (1.239-4.778) | 0.005 | ||
| Presence | 89 | - | - | - | - | |
| Absence | 86 | - | - | - | - | |
| DNMT3B expression | 1.236 (1.297-3.644) | 0.002 | 1.336 (1.079-2.847) | 0.001 | ||
| High | 57 | - | - | - | - | |
| Low | 118 | - | - | - | - | |