3.
肝癌各种影响因素对患者肿瘤特异性生存率的影响
Influence of different factors on tumor-specific survival rate of patients with HCC
| Variable | n | Univariate analysis | Multivariate analysis model | |||
| HR (95% CI) | P | HR (95% CI) | P | |||
| HR: Hazard ratio; CI: Confidence interval. | ||||||
| Gender | 0.608 (0.531-1.801) | 0.221 | - | - | ||
| Male | 89 | - | - | - | - | |
| Female | 86 | - | - | - | - | |
| Age (year) | 0.558 (0.304-1.517) | 0.489 | - | - | ||
| < 50 | 83 | - | - | - | - | |
| ≥50 | 92 | - | - | - | - | |
| AFP (ng/mL) | 1.290 (0.369-1.446) | 0.637 | - | - | ||
| ≤20 | 64 | - | - | - | - | |
| > 20 | 111 | - | - | - | - | |
| HBsAg | 1.670 (1.054-2.558) | 0.847 | - | - | ||
| Positive | 120 | - | - | - | - | |
| Negative | 55 | - | - | - | - | |
| Liver Cirrhosis | 0.984 (0.617-1.678) | 0.473 | - | - | ||
| Presence | 113 | - | - | - | - | |
| Absence | 62 | - | - | - | - | |
| TNM stage | 1.393 (0.831-1.967) | 0.843 | - | - | ||
| Ⅰ/Ⅱ | 89 | - | - | - | - | |
| Ⅲ/Ⅳ | 86 | - | - | - | - | |
| Tumor size (cm) | 1.060 (1.764-3.647) | 0.040 | 1.283 (1.178-3.617) | 0.013 | ||
| ≤5 | 77 | - | - | - | - | |
| > 5 | 98 | - | - | - | - | |
| Intrahepatic Metastasis | 1.476 (1.367-2.808) | 0.034 | 1.481 (0.647-2.714) | 0.020 | ||
| Presence | 99 | - | - | - | - | |
| Absence | 76 | - | - | - | - | |
| Vascular invasion | 1.696 (0.905-3.607) | 0.003 | 2.318 (1.763-5.078) | 0.015 | ||
| Presence | 89 | - | - | - | - | |
| Absence | 86 | - | - | - | - | |
| DNMT3B expression | 1.446 (1.891-4.804) | 0.012 | 1.660 (1.379-3.957) | 0.004 | ||
| High | 57 | - | - | - | - | |
| Low | 118 | - | - | - | - | |