Table 2. Therapeutic strategies for prevention of HCC recurrence after curative resection of HCC with MVI.
| Therapeutic strategy | Reference |
|---|---|
| Preoperative antiviral treatment for HBV | (15) |
| A wide margin of hepatic resection (≥1 cm) | (16) |
| Postoperative adjuvant transcatheter arterial chemoembolization | (2,17) |
| Postoperative adjuvant therapy with sorafenib | (18) |
| Postoperative adjuvant therapy with nivolumab (phase 3 clinical trial) | NCT03383458 |
HCC, hepatocellular carcinoma; MVI, microvascular invasion; HBV, hepatitis B virus.