Table 1.

A comparison between PathBank and other pathway databases

	PathBank	KEGG	Reactome	Wiki-Pathways	BioCarta
No. of organisms	10	6076	16	31	2
No. of pathways	110 234	653 007	20 882	2785	590
Ave. no. pathways/organism	1 1 023	107	1305	90	295
Protein pathways?	Yes	Yes	Yes	Yes	Yes
Metabolic pathways?	Yes	Yes	Yes	Yes	No
No. of pathways (Human)	48 701	335	2227	1,102	314
No. of pathways (E. coli)	1178	119	0	12	0
No. of pathways (A. thaliana)	3356	138	0	93	0
No. of pathways (Mouse)	12 651	331	1649	225	276
Hyperlinked proteins/genes	Yes	Yes	Yes	Yes	No
Hyperlinked metabolites	Yes	Yes	Yes	Yes	No
No. of disease pathways	20 692	91	411	118	5
No. of signaling pathways	64	65	718	211	39
No. of drug action pathways	404	75	46	39	0
Compound descriptions	Yes	No	No	No	No
Protein descriptions	Yes	No	No	No	No
Pathway summaries	Yes	Yes	Yes	Yes	No
Ave. word count per summary	342	68	179	143	0
Ave. ref. count per pathway	12	14	3	8	0
Rich visual display	Yes	No	Yes	No	Yes
Displays protein 4° structure	Yes	No	Yes	No	No
Displays metabolite structure	Yes	Yes	Yes	No	No
Displays cellular organelles	Yes	No	Yes	Yes	Yes
Displays cellular locations	Yes	No	Yes	Yes	Yes
Displays organs/tissues	Yes	No	Yes (in EHLDs)	No	No
Multicolored pathways	Yes	No	Yes	Yes	Yes
Multiple pathway views	Yes	No	No	No	No
No. pathway image formats	2	1	6	7	1
XML compatible	Yes	KGML	Yes	Yes	No
SBML compatible	Yes	No	Yes	Yes	No
BioPAX compatible	Yes	No	Yes	Yes	No
‘Google Maps’ interactivity	Yes	No	Yes	No	No
Community editable	Yes	No	No	Yes	No
Open access/Free download	Yes	No	Yes	Yes	Yes
Integrated with other DBs	Yes	Yes	Yes	Yes	No
Integrated with other Apps	Yes	Yes	Yes	Yes	No