Table 3.
Factor |
No. of patients N = 1 054a |
No. of VTE (%) N = 138 (13%) |
OR | 95% CI | P |
---|---|---|---|---|---|
RPLN 3.5 cm cutoffb | |||||
RPLN ≤3.5 cm | 931 | 42 (8%) | — | — | — |
RPLN >3.5 cm | 378 | 82 (22%) | 2.98 | 2.04, 4.34 | <.001 |
RPLN 5 cm cutoffc | |||||
RPLN ≤5 cm | 810 | 84 (10%) | — | — | — |
RPLN >5 cm | 243 | 54 (22%) | 2.6 | 1.77, 3.81 | <.001 |
Primary sited | |||||
Testicular primary | 979 | 118 (12%) | — | — | — |
Mediastinal primary | 27 | 6 (22%) | 2.16 | 0.78, 5.99 | .14 |
Retroperitoneal primary | 15 | 6 (40%) | 5.76 | 1.97, 16.82 | .001 |
IGCCCG Risk Classificatione | |||||
Good prognosis | 693 | 64 (9%) | — | — | — |
Intermediate prognosis | 204 | 31 (15%) | 1.72 | 1.08, 2.74 | .02 |
Poor prognosis | 155 | 43 (28%) | 3.26 | 2.06, 5.17 | <.001 |
LDH categoriesf | |||||
<1.5× ULN | 702 | 61 (9%) | — | — | — |
1.5‐ 5× ULN | 244 | 50 (20%) | 2.55 | 1.68, 2.74 | <.001 |
5‐10× ULN | 48 | 13 (27%) | 3.61 | 1.78, 7.32 | <.001 |
>10× ULN | 30 | 9 (30%) | 4.68 | 1.95, 11.22 | .001 |
LDH cutofff | |||||
<5× ULN | 946 | 111 (12%) | — | — | — |
>5× ULN | 78 | 22 (28%) | 2.92 | 1.70‐5.02 | <.001 |
Khorana scoreg | |||||
0‐2 | 882 | 105 (12%) | — | — | — |
>3 | 66 | 20 (30%) | 3.19 | 1.80, 5.64 | <.001 |
Hospitalizationh | |||||
No | 359 | 40 (11%) | — | — | — |
Yes | 413 | 64 (15%) | 1.44 | 0.94‐2.19 | .1 |
BSAi | |||||
<2 | 621 | 83 (13%) | — | — | — |
>2 | 414 | 52 (13%) | 0.9 | 0.62‐1.31 | .58 |
Vascular access devicej | |||||
No | 602 | 58 (10%) | — | — | |
Yes | 177 | 51 (29%) | 3.46 | 2.22, 5.40 | <.001 |
Renal functionk | |||||
CrCl >75 mL/min | 668 | 89 (13%) | — | — | — |
CrCl <75 mL/min | 51 | 16 (31%) | 3.48 | 1.87, 6.49 | <.001 |
Excludes patients who received prophylactic anticoagulation.
Unknown in 123 patients.
Unknown in 1 patient.
Unknown or other site in 33 patients.
Unknown in 2 patients.
Unknown in 30 patients.
Unknown in 106 patients.
Unknown in 277 patients.
Unknown in 81 patients.
Unknown in 275 patients.
Unknown in 335 patients.