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. 2019 Nov 22;48(1):63–74. doi: 10.1093/nar/gkz1099

Figure 1.

Figure 1.

(A) The two diastereoisomers of a phosphorothioate (PS) linkage. (B) Non-chiral 3′S and 5′S thiophosphate linkages. (C) Phosphoramidite building blocks for the synthesis of 3′S (19–30) and 5′S thiophosphate (31–38) linkages.