Table 3.

Diagnostic performance of cytology, UTC assay and the combined use of cytology and UTC assay

	Cytology	UTC	Cytology and UTC
Sensitivity
Total UC	40.2%	80.4%	84.1%
Low‐grade	18.9%	70.3%	75.7%
High‐grade	51.4%	85.7%	88.6%
Specificity
Total UC	98.6%	97.3%	95.9%
McNemar test of sensitivity
Total UC	<0.001		—
Low‐grade	<0.001		—
High‐grade	<0.001		—
Kappa value (P value)
Total UC	0.341 (<0.001)	0.746 (<0.001)	0.776 (<0.001)
Low‐grade	0.218 (0.004)	0.718 (<0.001)	0.745 (<0.001)
High‐grade	0.505 (<0.001)	0.832 (<0.001)	0.846 (<0.001)

Abbreviations: UC, urothelial carcinoma; UTC, urinary tumor cell.