Skip to main content
. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Biochim Biophys Acta Bioenerg. 2019 Nov 14;1861(2):148116. doi: 10.1016/j.bbabio.2019.148116

Figure 6. Structures of the C-terminus of wild-type, CiΔ6, and CiΔ16.

Figure 6.

The major structural changes in the CiΔ16 strain (PDB ID: 6PW1) were found in the T550 region. In the wild-type [12] and CiΔ6 (PDB ID: 6PW0) CytcOs, there are electron densities attributed to two water molecules or a metal ion (e.g. Mg2+) and a water molecule bound between T550 and H26. In CiΔ16, the loss of the last 16 residues of subunit I make T550 the new C-terminus. Here the T550 side chain is folded closer to H26, forming a hydrogen bond. This region is very close to the entrance of the D-pathway at residue D132.