Table 2.
Baseline geriatric assessment and quality-of-life measures (N=40)
| Domain | Measure | No. of Items |
Range of Scores | Mean ± SD | Median (Range) |
|---|---|---|---|---|---|
| Functional Status | Activities of Daily Living (subscale of MOS Physical Health) | 10 | 0-100 (higher score: better physical function) | 72.1±25.8 | 83.3 (50-94.4) |
| Instrumental Activities of Daily Living (subscale of the OARS) | 7 | 0-14 (higher score: less need for assistance) | 13.3±1.8 | 14 (4-14) | |
| *Karnofsky Self-Reported Performance Rating Scale | 1 | 40-100 (higher score: better function) | 83.2±15.1 | 90 (80-100) | |
| Karnofsky Physician-Reported Performance Rating Scale | 1 | 10-100 (higher score: better function) | 84.9±13.5 | 90 (50-100) | |
| Number of falls in last 6 months | 1 | Higher score, worse performance | 0.4 ±1.2 | 0 (0-7) | |
| Timed up and Go (seconds) | 1 | Higher score: worse performance) | 15.1±10 | 13 (5-60) | |
| Cognition | Blessed Orientation Memory and Concentration Test (BOMC) | 6 | 0-28 (score≥11 indicates impairment) | 3.1±3.0 | 2 (0-12) |
| Comorbidity | Physician Health Section Survey (subscale of the OARS) | 13 | 0-39 (higher score: greater comorbidity) | 3.2±3.1 | 2.5 (0-16) |
| HCT-CI | 17 | 0-29 (higher score: greater comorbidity) | 1.8±1.9 | 1.0 (0-7) | |
| Medications | *Number of medications | 1 | 4.5±3.7 | 4.0 (0-13) | |
| Psychological State | Mental Health Inventory-17 | 17 | 0-100 (higher score: better mental health) | 56.4±4.0 | 56.5 (49.4-67.1) |
| Social Activity | MOS Social Activity Survey | 4 | 0-100 (higher score: better social activity) | 60.3±21.8 | 62.5 (6.3-93.8) |
| Social Support | MOS Social Support Survey: Emotional Information and Tangible Subscales | 12 | 0-100 (higher score: better social support) | 83.5±16.4 | 92.3 (15.4-92.3) |
| Nutrition | *Percent unintentional weight loss in last 6 months | 1 | −1.9±11.7 | −1.9 (−53.8-21.7) | |
| Global Quality of life | EORTC QLQ C30 Global | 30 | 0-100 (higher score: better QOL) | 46.8±30.7 | 50 (0-100) |
Abbreviations: MOS=Medical Outcomes Survey; OARS=Older American Resources and Services; HCT-CI=Hematopoietic cell transplantation comorbidity index; EORTC QLQ=European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C-30; QOL=quality of life
*
Represents score for number of subjects completing this assessment: Patient reported KPS, N=37; Time up and go, N =35; number of falls, N = 36; number of medications, N = 33; percent weight loss, N=36.