Table 4.
Univariate association between baseline geriatric assessment measures and mortality
| Measure | Median Score Cut-point (N) | Hazard Ratio for Mortality (95% Confidence Interval) |
|---|---|---|
| Activities of Daily Living (subscale of MOS Physical Health) | ≤83.3 (18) | 1.6 (0.75-3.4) |
| >83.3 (21) | Reference | |
| Instrumental Activities of Daily Living (subscale of the OARS) | <14 (10) | 1.7 (0.75-3.7) |
| ≥ 14 (29) | Reference | |
| Number of falls in last 6 months | ≥1 (8) | 2.02 (0.87-4.69) |
| <1 (28) | Reference | |
| Karnofsky Self-Reported Performance Rating Scale | <90 (18) | 0.8 (0.4-1.7) |
| ≥90 (19) | Reference | |
| Karnofsky Physician-Reported Performance Rating Scale | <90 (15) | 0.7 (0.32-1.6) |
| ≥90 (24) | Reference | |
| Timed up and Go (seconds) | <13 (17) | 0.7 (0.32-1.53) |
| ≥ 13 (22) | Reference | |
| Blessed Orientation Memory and Concentration Test (BOMC) | ≤2 (24) | 0.8 (0.4-1.7) |
| > 2 (15) | Reference | |
| Physician Health Section Survey (subscale of the OARS) | ≤2.5 (19) | 0.9 (0.43-1.9) |
| >2.5 (19) | Reference | |
| HCT-CI | ≤1 (24) | 1.23 (0.6-2.7) |
| >1 (15) | Reference | |
| Number of medications | ≤4 (21) | 0.8 (0.3-1.8) |
| >4 (12) | Reference | |
| Mental Health Inventory-17 | <56.5 (24) | 0.7 (0.3-1.4) |
| ≥ 56.5 (15) | Reference | |
| MOS Social Activity Survey | ≤62.5 (22) | 0.7 (0.3-1.4) |
| >62.5 (17) | Reference | |
| MOS Social Support Survey | ≤92.3 (17) | 0.8 (0.4-1.6) |
| >92.3 (22) | Reference | |
| EORTC QLQ C30 Global | ≤50 (21) | 0.8 (0.3-1.7) |
| >50 (16) | Reference |
Abbreviations: MOS=Medical Outcomes Survey; OARS=Older American Resources and Services; HCT-CI=Hematopoietic cell transplantation comorbidity index; EORTC QLQ=European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C-30; QOL=quality of life