Table 2.

Summary partitioning free energies at 37°C of the 21-residue N-terminus peptide. Titration curves from which these data are obtained are provided in Figure 5B.

aLipid	bComposition	cKx ×10−3	dΔGwb
E. coli extract	—	224 ± 19	−7.6 ± 0.1
PC	—	en.o.	en.o.
PE:PC	50:50	13 ± 3.2	−5.8 ± 0.2
PE:PG	80:20	252 ± 29	−7.7 ± 0.1
PE:CL	80:20	281 ± 32	−7.7 ± 0.1

^aPC, palmitoyloleoylphosphatidylcholine (POPC); PE, palmitolyloleoylphosphatidylethanolamine (POPE); PG, palmitolyloleoylphosphatidylglycerol (POPG); CL, cardiolipin.

^bmole ratio.

^cmole-fraction partition coefficient (see Methods)

^dfree energy of transfer, water to bilayer, kcal mol⁻¹

^enot observable