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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Neuroscience. 2019 Nov 6;424:155–171. doi: 10.1016/j.neuroscience.2019.10.013

Table 2:

Prenatal ethanol exposure (2 g/kg/day, E10-E15) compared to control groups (n = 7/group) significantly increases the lateral hypothalamus the mRNA expression (measured using qRT-PCR) of CCR2 and MCH in both female and male embryos at E19, with the females showing a significantly greater effect, and of CCL2 mRNA in female embryos but not in male embryos. The data are represented here as mRNA percent change, based on average ratio scores of ethanol-treated embryos compared to the Untreated and Control groups. Data are mean ± SEM. *p < 0.05 versus control group. #, p < 0.05 versus males.

mRNA expression Female Male
Untreated Control Ethanol Untreated Control Ethanol
CCL2 100 ± 9.78 105 ± 5.07 173 ± 9.7*# 100 ± 9.78 103 ± 10.01 88 ± 9.98
CCR2 100 ± 7.19 107 ± 5.04 223 ± 4.71*# 100 ± 3.42 112 ± 5.08 139 ± 8.38*
MCH 100 ± 8.23 95 ± 7.27 191 ± 8.64*# 100 ± 7.09 102 ± 8.57 134 ± 7.14*