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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Neuroscience. 2019 Nov 6;424:155–171. doi: 10.1016/j.neuroscience.2019.10.013

Table 3:

Maternal administration of a CCR2 antagonist INCB3344 (1 mg/kg/day) during the period of prenatal ethanol exposure (2 g/kg/day, E10-E15) prevents the stimulatory effect of ethanol on CCL2, CCR2, and MCH mRNA in the LH of female E19 embryos (n = 7/group) as measured using qRT-PCR. The data are represented here as mRNA percent change, based on average ratio scores of ethanol-treated embryos compared to the Control group. Data are mean ± SEM. *p < 0.05 versus control group.

mRNA
expression		 Control Ethanol Ethanol+INCB3344 Control+INCB3344
CCL2 100 ± 5.08 175 ± 6.98* 118 ± 7.27 108 ± 4.06
CCR2 100 ± 4.11 226 ± 5.81* 107 ± 3.79 102 ± 4.61
MCH 100 ± 9.02 198 ± 8.99* 111 ± 3.25 117 ± 3.41