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. 2019 Nov 27;7(4):329–340. doi: 10.14218/JCTH.2019.00043

Table 4. Heavy metal** analysis and quantification in retrieved Ayurvedic samples.

Total samples, n = 42 Detected, n (%) Minimum* Maximum* Mean* Median* SD
Aluminum 7 (16.6%) 18.560 418.400 130.380 68.850 142.2248
Arsenic 29 (69.1%) 0.0100 119.430 13.963 0.400 33.3589
Gold 13 (30.9%) 0.0400 1.440 0.662 0.480 0.5816
Mercury 25 (59.5%) 0.0100 8.010 0.673 0.190 1.5854
Manganese 20 (47.6%) 0.640 824.170 74.031 19.720 182.0916
Nickel 33 (78.6%) 0.200 73.290 7.461 2.150 14.2936
Lead 36 (85.7%) 0.0800 73.370 7.129 1.465 13.7904
Thallium 18 (42.8%) 0.0100 2.400 0.432 0.250 0.5826
*

values in mg/kg.

**

the level below which there is low risk for human ill health for arsenic is 0.07 mg/kg; the permissible tolerable weekly intake (PTWI) for mercury is 1.6 µg/kg body weight; PTWI of aluminum is 1 mg/kg of body weight; tolerable upper limit of manganese is 11 mg per day; tolerable daily intake for nickel is 5 µg/kg body weight; permissible daily oral exposure (PDE) of gold is 134 µg/kg; PDE of lead is 5 µg per day and of thallium is 8 µg per day.

From U. S. Department of Health and Human Services Food and Drug Administration, Center for Drug Evaluation and Research (CDER) and Center for Biologics Evaluation and Research (CBER), Guidance for Industry 2015 update. Retrieved from https://www.fda.gov/regulatory-information/search-fda-guidance-documents/q3d-elemental-impurities on 3/10/2019.